Cristina "Tina" Negritto

Director and Associate Professor of Molecular Biology; On leave Fall 2021
  • Expertise

    Expertise

    Cristina Negritto studies genome maintenance mechanisms, particularly mechanisms involved in the repair of double strand breaks and how these can affect genome instability.

    Research Interests

    Genome maintenance mechanisms

    Areas of Expertise

    BIOLOGY

    • Yeast genetics and molecular biology
    • DNA repair
  • Work

    Work

    Negritto, M. C. (2010) "Repairing Double-Strand DNA Breaks," Nature Education 3(9):26

    Salim, H. M., Negritto M. C, Cavalcanti, A. R. (2009). "1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway." PLoS Genet 5(10): e1000701. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759508/?tool=pubmed

    Maria Cristina Negritto and Glenn Manthey. Overview of Blotting” Current Protocols Essential Laboratory Techniques (John Wiley & Sons, Inc. 2008), 8.1.1-8.1.19

    Negritto, M.C, J. Qiu, D.O. Ratay, B. Shen, and A.M. Bailis. 2001. Novel function of Rad27 (FEN-1) in restricting short-sequence recombination. Mol. Cell. Biol. 21: 2349-2358.

    Maines, S., M.C. Negritto, X. Wu, G.M. Manthey, and A.M. Bailis. 1998. Novel mutations in the RAD3 and SSL1 genes perturb genome stability. Genetics 150: 963-976.

    Negritto, M.C., X. Wu, T. Kuo, S. Chu, and A.M. Bailis. 1997. Influence of DNA sequence identity on efficiency of targeted gene replacement. Mol. Cell. Biol. 17: 278-286.

    Bailis, A.M., S. Maines, and M.C. Negritto. 1995. The essential helicase gene RAD3 suppresses short-sequence recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 3998-4008.

  • Education

    Education

    Ph.D.
    Beckman Research Institute of the City of Hope National Medical Center

     

    Licenciada, Facultad de Ciencias exactas y Naturales
    ​Universidad de Buenos Aires, Argentina

    Recent Courses Taught

    • Biochemistry and Molecular Biology of DNA Repair
    • Human Diseases with Defective Genome Maintenance Mechanisms
    • Molecular Biology with Lab
  • Awards & Honors

    Awards & Honors

    Pomona College, Wig Distinguished Professor Award for Excellence in Teaching, 2013