| Year | Speaker | Lecture |
|---|---|---|
| 2024 | Joseph S. Francisco | Science in the Sky: The Impactful Chemical Processes Above Us |
| 2023 | Melanie Sanford | 20 Years of Making Molecules at the University of Michigan |
| 2020 | Geraldine Richmond | The Importance of Science in the Future of a Healthy Planet |
| 2019 | Allison Campbell | Science in Service to our Nation: Unlocking the Mystery of the Department of Energy National Laboratories |
| 2018 | Paul Reider | Chemistry in Service to Society: Making Drugs for People, Not Profits |
| 2017 | JoAnne Stubbe | The Secrets of Biological Catalysts Revealed with Chemical and Spectroscopic Methods |
| 2016 | W.E. Moerner | Single Molecules as Nanoscale Probes of Our World |
| 2015 | Jack Szostak | The Origins of Cellular Life |
| 2014 | Robert Langer | Biomaterials and How They Will Change Our Lives |
| 2013 | Susan Solomon | Exploring Our Atmosphere's Climate and Chemistry |
| 2011 | J. Andrew McCammon | Computer-Aided Biophysics and Drug Discovery: From the Molecule to the Cell |
| 2010 | Peter Agre | Life on the River of Science |
| 2009 | Jean-Marie Lehn | Perspectives in Chemistry: From Supramolecular Chemistry Towards Adaptive Chemistry |
| 2009 | Jennifer Doudna | Chemistry and the RNA World |
| 2008 | Professor Sir Harold Kroto FRS | Science and Scientific Philosophy in the 21st Century |
| 2007 | Robert H. Grubbs | New Molecules, Materials, and Opportunities |
| 2006 | George M. Whitesides | Science at the Interface! |
| 2005 | Harry B. Gray | The Currents of Life: Electron Flow Through Biological Molecules |
| 2004 | Kurt Wuthrich | NMR Eyes on the Molecules of Life |
| 2003 | K. Barry Sharpless | Finding Something New and Useful |
| 2002 | Ahmed H. Zewail | Seeing Beyond Our Vision |
| 2000 | Paul S. Anderson | Understanding Drug Discovery |
| 1999 | George A. Olah | Hydrocarbons and their Chemistry |
| 1998 | Richard R. Ernst | Exploring Nature by NMR |
| 1997 | Stuart L. Schreiber | Chemical Genetics |
| 1996 | Sherwood Rowland | The Chemistry of Earth's Atmosphere |
| 1995 | Richard N. Zare | Shedding Light on Chemistry |
| 1994 | Thomas R. Cech | RNA Catalysis |
| 1993 | Heinrich Rohrer | Science for our Future |
| 1992 | Donald Cram | Molecular Recognition in Complexation |
| 1991 | Gertrude Elion | Chemotherapy - The Search of Selectivity |
| 1990 | Yuan Lee | Chemical Reaction Dynamics |
| 1989 | Jeremy Knowles | Enzymes |
| 1988 | Joseph Goldstein & Michael Brown | Revelations from Biochemistry and Human Genetics |
| 1987 | Herbert Brown | Boron in Organic Synthesis |
| 1986 | Roald Hoffman | Bridging Organic and Inorganic Chemistry |
| 1985 | Gerald Edelman | Sciences of Recognition |
| 1984 | Gabor Somorjai | Surface Science of Catalysis |
| 1983 | Paul Berg | Eucaryotic Gene Expression |
| 1982 | Sydney Brenner | Genetics of the Nervous System |
| 1981 | Christian Anfinsen | Structure and Function of Proteins |
| 1980 | Rosalyn Yalow | Radioimmunoassay |
| 1979 | Max Perutz | Hemoglobin |
| 1978 | William Lipscomb | Structure and Mechanisms of Enzymes |
| 1977 | David Baltimore | Molecular Genetics |
| 1976 | George Porter | Rapid Kinetics |
| 1975 | Julius Axelrod | Neurotransmitters |
| 1974 | Gerald Edelman | Molecular Immunology |
| 1973 | Efraim Racker | Electron Transport Coupled Phosphorylation |
| 1972 | Arthur Kornberg | DVA and Membrane Biochemistry |
| 1971 | George Wald | Vision |
| 1970 | Manfred Eigen | Dynamics of Biological Macromolecules |
| 1969 | Jacques Monod | Molecular Biology and the Kingdom of Ideas |
| 1968 | John Kendrew | The Structure of Proteins |
| 1967 | Marshall Nirenberg | Deciphering the Genetic Code |
| 1966 | Linus Pauling | The Structure of the Nucleus |
| 1965 | Francis Crick | The Structure of DNA |
| 1964 | David Green | Mitochondrion and Membrane Systems |
| 1963 | Peter Debye | The Nature of Molecular Forces |
| 1962 | Melvin Calvin | Photosynthesis |
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