The Pomona College Chemistry Department Presents
the 55th Robbins Lecture Series

"The Secrets of Biological Catalysts Revealed with Chemical and Spectroscopic Methods"

February 6-9, 2017

JoAnne Stubbe

Professor JoAnne Stubbe
Massachusetts Institute of Technology
2008 National Medal of Science

JoAnne Stubbe is the Novartis Professor of Chemistry, and Professor of Biology, at the Massachusetts Institute of Technology.  Her research has helped scientists understand the ways in which enzymes catalyze chemical reactions with rare accelerations over non-enzyme catalyzed reactions.  She has primarily focused on how nature harnesses the reactivity of free radicals to carry out difficult chemistry.  Her work has led to the design and synthesis of nucleotide analogs used in the treatment of various cancers.  Her earlier work revolutionized the biochemistry field with her first two scientific papers on the enzymes enolase and pyruvate kinase.

Prof. Stubbe received her B.S. in Chemistry from the University of Pennsylvania and her Ph.D. in Organic Chemistry from the University of California, Berkeley, in 1971.  Following a year of postdoctoral work at UCLA, she taught at Williams College, Yale University and the University of Wisconsin.  She became the first female tenure professor in the MIT Chemistry Department in 1987.

In 1992, she was elected to the National Academy of Science and was the recipient of the National Medal of Science in 2008 for her groundbreaking research in biochemistry and enzyme mechanism.

Monday, February 6, 2017, at 8:00 p.m.
“Ribonucleotide Reductases: Radical Enzymes with Suicidal Tendencies”
Tuesday, February 7, 2017 at 11:00 a.m.
“Use of Unnatural Amino Acids to Unravel a 35 Å Oxidation to Make DNA Building Blocks”
Wednesday, February 8, 2017 at 4:30 p.m.
“Non-Template Dependent Polymerizations to Form Polyhydroxybutyrates: Biodegradable Polymers with Properties of Thermoplastics”
Thursday, February 9, 2017 at 4:30 p.m.
“Bleomycins: Natural Product Therapeutics That Mediate Double Stranded DNA Cleavage”

The lecture series will be held at:
Seaver North Auditorium
645 N. College Avenue
Claremont, California

(The cross streets are College Avenue & 7th Street)

All lectures are free and open to the public.