The Pomona College Chemistry Department Presents
the 55th Robbins Lecture Series
JoAnne Stubbe is the Novartis Professor of Chemistry, and Professor of Biology, at the Massachusetts Institute of Technology. Her research has helped scientists understand the ways in which enzymes catalyze chemical reactions with rare accelerations over non-enzyme catalyzed reactions. She has primarily focused on how nature harnesses the reactivity of free radicals to carry out difficult chemistry with exquisite specificity by focusing mostly on the mechanism of nucleotide reductases, the enzymes responsible for the biosynthesis of the deoxyribonucleotide building blocks required for DNA biosynthesis. Her work has led to the design and synthesis of nucleotide analogs used in the treatment of various cancers. Her earlier work revolutionized the biochemistry field with her first two scientific papers on the enzymes enolase and pyruvate kinase.
Prof. Stubbe received her B.S. in Chemistry from the University of Pennsylvania and her Ph.D. in Organic Chemistry from the University of California, Berkeley in 1971. Following a year of postdoctoral work at UCLA, she taught at Williams College, Yale University and the University of Wisconsin. She became the first female tenure professor in the MIT Chemistry Department in 1987.
In 1992, she was elected to the National Academy of Science and was the recipient of the National Medal of Science in 2008 for her groundbreaking research in biochemistry and enzyme mechanism. This was followed in 2010, by Prof. Stubbe receiving the Welch Award in 2010 for chemical research contributions having a significant, positive influence on mankind and in 2012 with the Killian Faculty Award, MIT’s highest faculty award recognizing her scientific leadership, pioneering work and inspiring teaching.
"The Secrets of Biological Catalysts Revealed with Chemical and Spectroscopic Methods"
February 6-9, 2017
Professor JoAnne Stubbe
Massachusetts Institute of Technology
2008 National Medal of Science
Monday, February 6, 2017, at 8:00 p.m.
“Radicals: Your Life is in Their Hands"
Tuesday, February 7, 2017 at 11:00 a.m.
“Unnatural Amino Acids to Probe an Unprecedented 35 Å oxidation in Biology"
Wednesday, February 8, 2017 at 4:30 p.m.
“Gemcitabine and Clofarabine, Cancer Therapeutics, Target Ribonucleotide Reductase"
Thursday, February 9, 2017 at 4:30 p.m.
“Polyhydroxyalkanoates: Biodegradable Polymers with Properties of Thermoplastics"
The lecture series will be held at:
Seaver North Auditorium
645 N. College Avenue
(The cross streets are College Avenue & 7th Street)
All lectures are free and open to the public.